Aji Agung Cahyaji. PENGARUH AROMATERAPI MINYAK ATSIRI JAHE TERHADAP KADAR TRIGLISERIDA DAN KOLESTEROL DARAH TIKUS YANG DIBERI PAKAN TINGGI LEMAK. B04080098. Skripsi. 2013. Pembimbing: Hera Maheshwari, Siti Sa’diah

PENGARUH AROMATERAPI MINYAK ATSIRI JAHE TERHADAP KADAR TRIGLISERIDA DAN KOLESTEROL DARAH TIKUS YANG DIBERI PAKAN TINGGI LEMAK

(The Effect of Ginger Essential Oil Aromatherapy on Blood Triglyceride and Cholesterol Level of Rats That Fed High Fat Diet)

AJI AGUNG CAHYAJI, HERA MAHESHWARI, SITI SA’DIAH

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ABSTRAK

Penelitian ini bertujuan untuk mengkaji pengaruh minyak atsiri jahe yang diaplikasikan perinhalasi terhadap kadar kolesterol total, trigliserida, kolesterol High Density Lipoprotein (HDL), dan kolesterol Low Density Lipoprotein (LDL) serum darah tikus yang diberi diet tinggi lemak. Delapan belas tikus putih dibagi kedalam tiga kelompok perlakuan. Kelompok perlakuan K1 (diberi pakan standar) sebagai kontrol negatif, K2 (diberi pakan tinggi lemak) sebagai kontrol positif, dan K3 (diberi pakan tinggi lemak dan inhalasi minyak atsiri jahe). Pengambilan darah dilakukan setelah 5 minggu perlakuan, kemudian dipisahkan serumnya. Trigliserida, kolesterol, kolsterol HDL, dan kolesterol LDL diukur kadarnya melalui pengujian serum. Hasilnya menunjukkan bahwa kelompok perlakuan K3 memiliki kadar trigliserida, kolesterol total, dan kolesterol LDL yang lebih rendah dibandingkan kelompok K2. Kadar kolesterol HDL kelompok perlakuan K3 lebih tinggi dibandingkan kelompok K2. Dari hasil tersebut dapat disimpulkan bahwa inhalasi minyak atsiri jahe dapat menurunkan kadar trigliserida, kolesterol total, dan kolesterol LDL, serta dapat meningkatkan kadar kolesterol HDL.

Kata kunci: trigliserida, kolesterol, kolesterol LDL, kolesterol HDL, minyak atsiri jahe.

ABSTRACT

The study aims to determine the effect of ginger (Zingiber officinale) essential oil via inhalation on blood triglyceride, total cholesterol, High Density Lipoprotein (HDL) cholesterol, and Low Density Lipoprotein (LDL) cholesterol level of rats that fed high fat diet. Eighteen albino rats (Rattus norvegicus) were devided into three treatments groups. The treatments were K1 (standard diet) as negative control, K2 (high fat diet) as positive control, and K3 (high fat diet + ginger essential oil inhalation). Blood samples were collected after 5 weeks of treatment period. The result showed the level of triglyceride, cholesterol, and HDL cholesterol at treatment K3 tend to be lower than treatment K2. LDL cholesterol level at treatment K3 show higher result than treatment K2. From the result of this study cocluded that inhalation of ginger essential oil can lowering triglyceride, total cholesterol, and LDL cholesterol level and raise HDL cholesterol level.

Keywords: triglyceride, cholesterol, HDL cholesterol, LDL cholesterol, ginger essential oil

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